Collateral Major in Molecular Biology
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Molecular Biology at Coe College

The collateral concentration in Molecular Biology offers hands-on experience and advanced course work in this cutting edge field. The collateral concentration gives students interested in careers in molecular biology, molecular genetics, biomedical research, medicine and biochemistry the chance to gain considerable practical knowledge and experience. Students may start with either a major in Biology or Chemistry and then take the set of courses, outlined below, providing additional depth in the concentration in addition to their core degree. Coe College recognizes this career area as one of almost unlimited potential. Most of the cutting edge research today, and for the foreseeable future, is being done in the broad category of Molecular Biology/Biochemistry. We have committed ourselves to providing our students with professional quality equipment and "real world" laboratory experiences to make them competitive as future twenty first century scientists.

Students will take a course called Techniques in Molecular Biology before, or during, the junior year. This course provides students an applied and theoretical knowledge of the most common concepts and bench techniques in molecular biology. Usually, in the summer of the junior year, collateral students are strongly encouraged to participate in summer research. Students who have completed the core courses have worked with faculty on a variety of research projects on campus. A number of the strongest students have proven to be unusually successful in winning nationally competitive NSF and Howard Hughes Foundation grants, with stipends, to do summer research on campuses at major research institutions across the United States. These students have generally gone on to write excellent honors theses and have gained admission into outstanding graduate programs, professional schools or have gone onto successful careers in industrial or academic research.

Requirements for a collateral major in Molecular Biology.

The completion of the requirements for a major in Biology and,

CHM-185 Organic Chemistry 1
CHM-225 Organic Chemistry 2
CHM-235 Organic Chemistry Laboratory
BIO-345 Techniques in Molecular Biology*
BIO-340 Techniques in Molecular Biology Laboratory
CHM-405 Biochemistry
BIO-405 Current Topics in Molecular Biology
And completion of one of the following courses--
BIO-525 and 520 Bacteriology and Laboratory.
**This option is for those interested in prokaryotic biology.
BIO-515 and 510 Cell Physiology and Laboratory.
**This option is for those interested in eukaryotic biology.
Strongly recommended are two physics courses;
either PHY-115 and 135 or PHY-216 and 226.
Also, strongly recommended BIO -845/, (Research Participation)
and/or BIO or 8_5 (Independent Study/Honors) be a component
of the collateral degree.


The key course in the collateral major is
BIO-345/340: Techniques in Molecular Biology.
*An intensive introduction to biological molecular techniques. Students learn how to manipulate recombinant DNA and express and detect protein products in prokaryotic systems. Course methods include cloning, restriction mapping, ligation, labeling purification, elution, blotting, hybridization, agarose and polyacrylamide gels, protein expression and detection and immunological techniques. On completing the course students should have a working knowledge of most methods used in molecular biology research. Prerequisites: Introduction to Cellular and Molecular Biology (BIO-145), Principles of Structural Chemistry (CHM-155), Principles of Chemical Reactivity


About Coe's program:

The Collateral Major has been supported by generous National Science Foundation grants for equipment and a major Carver Foundation Grant of nearly $100,000.00 also dedicated to equipment purchase for molecular biology/biochemistry. Thus, this program has all the basic, and much of the more specialized, pieces of equipment required for sophisticated experimentation in cellular and molecular biology and biochemistry. We are so committed to exposing our students to new technology that they are introduced to the use of appropriate pieces of this equipment in their very first laboratory experiences. The college has hired faculty with expertise in various fields allied to molecular biology and biochemistry. The college has als provided summer grant money available to students and faculty to pursue research interests as well as the operating budget necessary to support courses at a high level.

We are also dedicated to assisting qualified students in finding research opportunities. While we can provide fine research opportunities on campus, we cannot provide the same type of research environment that is found at major research institutions for which our students will attend at the next stage of their careers. Students with good grade points, who have taken the technical courses, are getting summer placements in excellent research laboratories across the nation.

The Faculty: Advisors in the Molecular Biology Collateral Major

Dr. Tom Tauer, Program Coordinator
Dr. Maria Dean


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Coe College 1999

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